5月22日美国印第安纳大学-普渡大学（印第安纳波利斯）陈杰教授讲座预告

    报告题目：牙齿正畸的挑战—多学科工程问题
    报 告 人：陈杰教授  美国印第安纳大学-普渡大学（印第安纳波利斯）机械工程系
    报告时间：2017年5月22日（星期一）下午14:00-15:30
    报告地点：特种装备与先进加工技术教育部重点实验室（朝晖校区北门）A220
    报告摘要：这项研究的长期目标是提高正畸临床治疗效果的可预测性。重点是减少正畸治疗引起的副作用，提高治疗效率，有利于临床医生和患者。治疗的可预测性依赖于控制良好的治疗方案、对牙齿移动机制以及生物反应的理解、矫治器械的优化设计以及临床结果的评估能力。工程技术已经发展到可以对临床上的三维施力系统进行定量控制；以及研究生物反应的炎症水平、骨成型/骨重建以及基因型，以确定主导控制参数；通过工程技术，也可以使矫治器械设计满足临床需要，并对不同治疗时间的临床结果进行量化预测，包括牙齿移动量、治疗的副作用如牙根吸收等。另外，还研究了加速牙齿移动的方法。 这些研究成果将对牙齿在正畸矫治力下的移动分析提供证据，并对减少正畸治疗中医源性副作用提供对策，从而进一步为优化治疗方案的制订提供证据支持。基于这些研究成果设计的正畸矫治器将会减少副作用，提高治疗效率，并将为优化其他正畸矫治技术提供创新的力学基础。这是通过多学科方法系统地解决工程问题的一个例子。
    报告人简介：
    陈杰教授现任美国印第安纳大学-普渡大学（印第安纳波利斯）（IUPUI）普渡工程与技术学院机械工程系主任。他于1982年毕业于天津大学获机械工程学士学位，1985年获得上海第二医科大学生物医学工程专业硕士学位，1989年获得美国Drexel大学机械工程与力学专业博士学位。1989年至1991年在Drexel大学机械工程与力学系做博士后。1990年8月加入IUPUI，任职机械工程系（80% ）和口腔正畸系（20%）双聘助理教授，1995年升为副教授，2000年升为教授。
陈杰教授的研究领域包括电池系统、机械系统建模、应力分析、计算机辅助工程、设计和生物力学。他的研究涉及到大量的工程应用包括生物系统、混合动力汽车能量系统等。陈杰教授累计发表了100多篇论文。他作为项目负责人（PI），累计获得超过900万美元的研究资助，他的研究得到政府机构的支持，如美国国防高级研究计划局（DARPA）、美国国防部（DOD）、美国能源部（DOE）、美国国立卫生研究院（NIH），也得到了私人基金会如惠特克基金会（Whitaker Foundation）和工业界的支持。他目前正在指导由美国能源部主办的印第安纳工业评估中心。

Orthodontic challenge-A multidisciplinary engineering problem

    ABSTRACT
    The long term goal of this research is to make clinical orthodontic treatment outcomes more predictable. The focuses are on reducing the orthodontic treatment induced side-effects and increasing treatment efficiency, which benefit both clinicians and patients.  The predictability relies on well-controlled treatment strategies, understanding of the mechanism of tooth movements as well as biological responses, optimal design of appliances, and the ability to evaluate clinical outcomes.  Engineering technologies have been developed to control the strategies in terms of quantification of clinical three dimensional load systems; to study the biological response in terms of inflammation level, bone modeling/remodeling, and genotypes in order to identify the dominant control parameters; design of appliance to meet the clinical needs; and to quantify the clinical outcomes in terms of treatment time, tooth movement, and side-effects, such as root resorption. The methods to accelerate tooth movements are also investigated. The outcomes of this research will provide the evidence as how the tooth moves in response to the applied orthodontic load. The study will also provide insight into ways of reducing iatrogenic side-effects and into the necessary evidence-based trade-offs for optimized treatment.  With the knowledge gained, future orthodontic appliances will be designed to reduce side-effects and to make treatment more efficient.  Furthermore, these results will provide a foundation for innovative mechanics that optimizes other orthodontic treatments. This is an example of how to systematically solving engineering problems through multidisciplinary approach.

    BRIEF BIO
    Dr. Chen received BSME degree from Tianjin University, P.R. China, in 1982, MS degree in Biomedical Engineering from Shanghai Second Medical University, P.R. China, in 1985 and Ph.D. from Drexel University in Mechanical Engineering and Mechanics, in 1989. He was a postdoctoral fellow in the Department of Mechanical Engineering and Mechanics, Drexel University, from 1989 to 1990. He joined IUPUI in August of 1990 as assistant Professor in Mechanical Engineering (80%) and Orthodontics (20%). He was promoted to Associate Professor in 1995 and to Professor in 2000. Dr. Chen currently serves as the Chair of the Department of Mechanical Engineering, Purdue School of Engineering and Technology, at IUPUI.
    Dr. Chen's research interests include battery system, mechanical system modeling, stress analysis, computer-aided-engineering, design, and biomechanics. He has been dealing with various engineering applications ranging from biological systems to power train of hybrid electric vehicle. Dr. Chen has published more than 100 publications. He served as the Principal Investigator for more than $9M research grants. His research has been supported by government agencies, such as, DARPA, DOD, DOE, NIH, the private foundations, such as the Whitaker Foundation, and industries. He is currently directing the Indiana Industrial Assessment Center sponsored by DoE.